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LUNGClear
FAQs and Datasheet

LUNGClear

Up to 83% of stage 1 cancer cases detected 1

LUNGClear is a convenient blood test that detects a molecular signature associated with lung cancer. It also avoids the risks of radiation exposure associated with LDCT scans.

LUNGClear

Blood Test for Early Detection of Lung Cancer

Clinical Studies

1 in 5 cancer deaths are due to lung cancer

Lung cancer is the most diagnosed cancer globally.2

It is the leading cause of cancer death in Southeast Asia.2

The high mortality rate is driven primarily by late-stage diagnosis.3

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Early detection improves lung cancer survival

Early detection can reduce lung cancer deaths, as it increases the likelihood of successful treatment.4

Someone diagnosed with stage 1 lung cancer is about 13x more likely to survive five years post-diagnosis than someone diagnosed at stage 4.5

Current lung cancer screening practice

The most established method of lung cancer screening is low-dose computed tomography (LDCT), which uses x-rays to produce images of your lungs.6

How does LUNGClear help with lung cancer detection?

LUNGClear is a convenient blood test that detects a molecular signature associated with lung cancer. It also avoids the risks of radiation exposure associated with LDCT scans.

The test reports a risk score, indicating whether you are at low, intermediate or high risk of having lung cancer at the time of testing.

The LUNGClear report will be assessed by your doctor, and he/she will propose the next course of action, if necessary.

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Who is at risk of developing lung cancer?
Smoke or used to smoke cigarettes

Smoking is the leading cause of lung cancer, even if you quit years ago.

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Exposed to secondhand smoke

Regular exposure to others’ smoke can also increase risk.

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Family history of lung cancer

Having a close relative with lung cancer may raise your chances.

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However, you can still develop lung cancer even without any of the above risk factors:
  • About one-third of all lung cancer patients in East Asia have never smoked.7
  • Among women in Asia with lung cancer, non-smokers outnumber smokers.4
Frequently Asked Questions

Early-stage lung cancer commonly does not cause symptoms. When it does, those symptoms are usually similar to other less serious illnesses, such as coughing, loss of appetite or chest discomfort.

An LDCT scan is a procedure that uses x-rays to take a series of images of areas inside your body while you are lying down. These images can be used to create 3D views of internal organs. It is commonly used for detecting lung cancer in persons who are at high risk, such as long-term heavy smokers.

LUNGClear is intended for healthy individuals aged 40 and above, who are not at high risk of lung cancer.

LUNGClear is a simple and convenient blood test in which about 5 mL of your blood is drawn into a tube and sent for analysis.

A report describing your risk score and risk category for having lung cancer at the time of testing will be sent to the ordering physician. He/she will go through the report with you, including whether further evaluation is advisable.

References

1 In clinical validation studies conducted by Mirxes
2 Global Cancer Observatory, International Agency for Research on Cancer, World Health Organization.
3 Caballero-Vázquez A, et al. Risk Factors for Short-Term Lung Cancer Survival. J Clin Med. 2021 Feb 1;10(3):519.
4 Lam, D. C.-L. et al. (2023). Lung Cancer Screening in Asia: An Expert Consensus Report. Journal of Thoracic Oncology, 18(10), 1303–1322.
5 Cancer Research UK, Survival for lung cancer.
6 Screening for Lung Cancer, Division of Cancer Prevention and Control, US Centers for Disease Control and Prevention.
7 Zhou, F., & Zhou, C. (2018). Lung cancer in never smokers—the East Asian experience. Translational Lung Cancer Research, 7(4), 450–463.

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