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ID3EAL™ PanoramiR miRNA Knowledge Panel

Minimal Input, Maximum Insight

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ID3EAL™ PanoramiR Knowledge Panel

The ID3EAL™ PanoramiR Knowledge Panel is an effective approach for profiling miRNAs important in biological processes, disease mechanisms, or biomarker discovery for clinical applications such as disease diagnosis and prognosis, disease stratification or treatment selection.

PanoramiR targets 376 miRNAs expertly curated from miRBase 22, HMDD 3.2 and TCGA. This is further cross-referenced with high-impact publications and in-house research data.

Benefits of PanoramiR miRNA Knowledge Panel

- Expertly curated disease associated panel generates meaningful insights.
- Highly sensitive and robust technology detects lowly expressed miRNAs with minimal sample input.
- Relevance to over 20 diseases including cancers, dementias, cardiovascular disease, liver diseases and more.
- Relevance to various sample types including plasma, serum and solid tissues.

- Ready-to-use qPCR plate with pre-spotted primers
- Pre-wet lab validated multiplexed RT primer pools and qPCR assays
- Reagents pre-aliquoted into experimentally relevant proportions
- Spike-in RNA controls included
- Semi-automated data analysis template for normalization, fold-change results and data visualizations

- RNA-to-Ct in 3 hours to 4 hours with a pre-amplification step to enhance detection with very limiting amounts of starting material.

A Panorama of Pathologies

Category	Examples	microRNA Targets
Cardiovascular	Cardiovascular Disease (e.g. stroke, coronary artery diseases, etc)	140
Metabolic	Diabetes, Liver Cancer	358
Neurological	Alzheimer’s Disease, Dementia, Depression, CNS Cancer	114
Respiratory	Lung Disease, Lung Cancer	165
Urological	Kidney Disease, Bladder Cancer	51
Reproductive	Cervical Cancer, Prostate Cancer	319
Gastrointestinal	Stomach Cancer, Colorectal Cancer	224
Hematological	Leukemia, Lymphoma	150

References

Key principles of miRNA involvement in human diseases. Discoveries (Craiova). 2014 Oct-Dec; 2(4): e34.

Ordering Information

Product	No. of Targets	Contents	Pack Size	Catalogue No.
ID3EAL™ PanoramiR miRNA Knowledge Panel	376	RT primers, PCR plates, Spike-In. cDNA synthesis and qPCR master mixes are included.	12 Samples	FGS0003R

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Email: sales@mirxes.com

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